Endocrine Abstracts

We describe case of 29-year woman with no concomitant illneses in her history and with negative family history in sense of adrenal or cancer disease.She came first in February 2012 for secondary hypomenorrhea lasting for 3 months, hirsutism and worsening of acne. Laboratory examination reveals markedly elevated free testosterone (9.6 nmol/l) and slightly elevated morning cortisol (687.4 nmol/l) with almost no suppresion in low dose dexamethasone suppresi...

Introduction: Adrenal incidentaloma is a problem with increasing importance. There are CT-density and washout criteria for distinction between adrenal adenoma and other tumours, there are well established protocol of screening for malignancy and/or hormonal dysfunction. But there remains small portion of atypical adenoma where detailed diagnostic is needed. One relatively new option is endosonography-guided fine-needle aspiration biopsy.Aim: To assess va...

Introduction: Isolated maternal hypothyroxinemia leads to higher prevalence of children autism, attention-deficit/hyperactivity disorder and mild cognitive deficiency. Frequency of hypothyroxinemia among women with gestational diabetes mellitus (GDM) is unclear and routine screening is not well established.Objective: Find prevalence of maternal isolated hypothyroxinemia in women with GDM and assess relations with necessity of insulinotherapy.<p class...

Acromegaly is usually diagnosed after several years of duration. The multimodal therapy – surgery, radiotherpy, pharmacotherapy – is necessary in the majority of patients. Register of sellar tumors (RESET) collecting data of patients from eight tertiary centers in the Czech and Slovak Republics since the year 2000 was established in 2008.Aim of analysis: Evaluation of diagnostics of acromegaly and effectiveness of its treatment in a daily pract...